Expression and localization of interleukin 1 beta and interleukin 1 receptor (type I) in the bovine endometrium and embryo

Cytokines, initially identified as peptides and protein secretory products of immune cells, play important roles in the endometrial physiology and maternal regulation of embryonic development (Robertson et al., 1992; Singh et al., 2011). In mammals, deregulated expression of cytokines can lead to total or partial failure of implantation and abnormal placental formation (Guzeloglu-Kayisli et al., 2009).

Source: Journal of Reproductive Immunology - April 15, 2015 Category: Allergy & Immunology Authors: Eva Correia-Álvarez, Enrique Gómez, David Martín, Susana Carrocera, Silvia Pérez, Jesús Otero, Nathalie Peynot, Corinne Giraud-Delville, José Néstor Caamaño, Olivier Sandra, Véronique Duranthon, Marta Muñoz Source Type: research