Endocrine and pubertal disturbances in optic nerve hypoplasia, from infancy to adolescence

Conclusions: A significant proportion of children with ONH have endocrine dysfunction. The high frequency of pubertal disturbances in this study emphasizes the need for long-term monitoring of developing endocrinopathy. While pituitary gland abnormalities are a good predictor of endocrine dysfunction, a normal pituitary gland does not rule out endocrinopathy.
Source: International Journal of Pediatric Endocrinology - Category: Endocrinology Authors: Source Type: research