Blood SC5b-9 complement levels increase at parturition during term and preterm labor

Parturition is a physiological process that requires the synchronization of uterine contractions, cervical dilatation, and membrane rupture. Several reviews have emphasized that the physiological phenomena, molecules, and cellular mechanisms that drive the process of human parturition are not completely understood (Breuiller-Fouche and Germain, 2006). The complement system is an important effector of the immune system because it forms pores in cell membranes that lead to cell lysis; thus, the complement system is thought to play a crucial role during parturition.
Source: Journal of Reproductive Immunology - Category: Allergy & Immunology Authors: Source Type: research