Interleukin-4 −590 T>C and interleukin-4 receptor Q551R A>G gene polymorphisms in Saudi cases with alopecia areata

Conclusion: IL-4 −590 and IL-4RQ551R gene polymorphisms are not associated with the susceptibility and the clinical pattern of AA in Saudi patients. We recommend further research studies involving the estimation of cytokines both in the serum and in the local skin lesions or in cultured skin cells to figure out whether Th1 or Th2 pathways play a specific role in the pathogenesis of AA.
Source: The Journal Of The Egyptian Public Health Association - Category: Global & Universal Tags: Original articles Source Type: research