CIDP‐like neuropathies in graft versus host disease

This study reviews the literature data and reports one additional case. Materials and MethodsA systematic review of the CIDP‐like neuropathies associated with GVHD was conducted until January 2015, analyzing the clinical presentation and the response to different therapeutic regimens. ResultsNineteen patients with CIDP‐like neuropathies associated with GVHD have been reported in literature including the present one. Fourteen subjects fulfilled the criteria for CIDP, while two cases presented with an asymmetric motor onset and one showed motor involvement only associated with anti‐ganglioside antibodies. In addition, two subjects already affected by CIDP developed a significant relapse after GVHD. DiscussionThis study reviews the literature data and reports one additional case of CIDP and GVHD, suggesting that the two clinical entities might share a similar immunological background.
Source: Journal of the Peripheral Nervous System - Category: Neurology Authors: Tags: Review Source Type: research