Expression of the ALS-causing variant hSOD1G93A leads to an impaired integrity and altered regulation of claudin-5 expression in an in vitro blood–spinal cord barrier model

Expression of the ALS-causing variant hSOD1G93A leads to an impaired integrity and altered regulation of claudin-5 expression in an in vitro blood–spinal cord barrier model

Journal of Cerebral Blood Flow & Metabolism advance online publication, April 8 2015.
doi:10.1038/jcbfm.2015.57

Authors: Sabrina Meister, Steffen E Storck, Erik Hameister, Christian Behl, Sascha Weggen, Albrecht M Clement & Claus U Pietrzik

Source: Journal of Cerebral Blood Flow - April 8, 2015 Category: Neurology Authors: Sabrina MeisterSteffen E StorckErik HameisterChristian BehlSascha WeggenAlbrecht M ClementClaus U Pietrzik Tags: amyotrophic lateral sclerosis blood–spinal cord barrier forkhead box protein O1 superoxide dismutase tight junctions Source Type: research